Is HSDB 8316 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use HSDB 8316? Is HSDB 8316 safe for nursing mother and child? Does HSDB 8316 extracts into breast milk? Does HSDB 8316 has any long term or short term side effects on infants? Can HSDB 8316 influence milk supply or can HSDB 8316 decrease milk supply in lactating mothers?
HSDB 8316 lactation summary
- DrLact safety Score for HSDB 8316 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of HSDB 8316 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that HSDB 8316 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of HSDB 8316 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using HSDB 8316 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About HSDB 8316 usage in lactation
One case with no traces of this drug in the mother's milk has been reported. Until more information is available, safer options should be preferred.
Answer by DrLact: About HSDB 8316 usage in lactation
Because there is little published experience with HSDB 8316 during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.
HSDB 8316 Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking HSDB 8316.[3] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics have caused adverse effects in breastfed newborns.[4][5]
HSDB 8316 Possible Effects in Breastfeeding
A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[6] Relevant published information on the effects of beta-blockade or HSDB 8316 during normal lactation was not found as of the revision date.
Alternate Drugs
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nebivolol(Unsafe)
Nadolol(Unsafe)
Carvedilol(Low Risk)
Timolol(Safe)
Metoprolol(Safe)
Bisoprolol(Low Risk)
Sotalol(Low Risk)
Propranolol(Safe)
Atenolol(Unsafe)
Procainamide(Safe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Flecainide(Safe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
Lidocaine(Safe)
Timolol(Safe)
Mexiletine(Safe)
Metoprolol(Safe)
Disopyramide(Safe)
Bisoprolol(Low Risk)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Propafenone(Low Risk)
Propranolol(Safe)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Levobunolol(Low Risk)
Bumetanide(Low Risk)
Doxazosin(Safe)
Hydrochlorothiazide(Safe)
Hydralazine(Safe)
Bosentan(Low Risk)
Nitrendipine(Safe)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Labetalol(Safe)
Nisoldipine(Low Risk)
Bendroflumethiazide(Unsafe)
Fosinopril(Low Risk)
Nebivolol(Unsafe)
Nimodipine(Safe)
Benazepril(Safe)
Verapamil(Safe)
Nifedipine(Safe)
Amlodipine(Low Risk)
Nicardipine(Safe)
Felodipine(Low Risk)
Trandolapril(Dangerous)
Valsartan(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Terazosin(Unsafe)
Telmisartan(Unsafe)
Spironolactone(Safe)
Timolol(Safe)
Prazosin(Unsafe)
Methyldopa(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Ramipril(Low Risk)
Lisinopril(Low Risk)
Sotalol(Low Risk)
Losartan(Low Risk)
Isradipine(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Indapamide(Low Risk)
Chlorothiazide(Safe)