Is Osimertinib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Osimertinib? Is Osimertinib safe for nursing mother and child? Does Osimertinib extracts into breast milk? Does Osimertinib has any long term or short term side effects on infants? Can Osimertinib influence milk supply or can Osimertinib decrease milk supply in lactating mothers?
Answer by DrLact: About Osimertinib usage in lactation
No information is available on the clinical use of osimertinib during breastfeeding. Because osimertinib is 95% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 48 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during osimertinib therapy and for 2 weeks after the final dose.
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