Question

I am a breastfeeding mother and i want to know if it is safe to use Ruxolitinib? Is Ruxolitinib safe for nursing mother and child? Does Ruxolitinib extracts into breast milk? Does Ruxolitinib has any long term or short term side effects on infants? Can Ruxolitinib influence milk supply or can Ruxolitinib decrease milk supply in lactating mothers?

Answer by DrLact: About Ruxolitinib usage in lactation

No information is available on the clinical use of ruxolitinib during breastfeeding. Because ruxolitinib is 97% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during ruxolitinib therapy and for 2 weeks after the last dose.

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