Is Vemurafenib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Vemurafenib? Is Vemurafenib safe for nursing mother and child? Does Vemurafenib extracts into breast milk? Does Vemurafenib has any long term or short term side effects on infants? Can Vemurafenib influence milk supply or can Vemurafenib decrease milk supply in lactating mothers?
Answer by DrLact: About Vemurafenib usage in lactation
No information is available on the clinical use of vemurafenib during breastfeeding. Because vemurafenib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 57 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during vemurafenib therapy and for 2 weeks after the final dose.
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