Is Vandetanib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Vandetanib? Is Vandetanib safe for nursing mother and child? Does Vandetanib extracts into breast milk? Does Vandetanib has any long term or short term side effects on infants? Can Vandetanib influence milk supply or can Vandetanib decrease milk supply in lactating mothers?
Answer by DrLact: About Vandetanib usage in lactation
No information is available on the clinical use of vandetanib during breastfeeding. Because vandetanib is 90% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 19 days and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during vandetanib therapy and for 4 months after the last dose.
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