Question

I am a breastfeeding mother and i want to know if it is safe to use Sopaquin? Is Sopaquin safe for nursing mother and child? Does Sopaquin extracts into breast milk? Does Sopaquin has any long term or short term side effects on infants? Can Sopaquin influence milk supply or can Sopaquin decrease milk supply in lactating mothers?

Sopaquin lactation summary

Sopaquin is safe in breastfeeding
  • DrLact safety Score for Sopaquin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Sopaquin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Sopaquin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Sopaquin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Sopaquin usage in lactation

No adverse effect has been described. Anti-malarial drug used for anti-inflammatory and immune suppressive medication on collagen diseases like idiopathic arthritis or lupus. After a dose of 5 mg per kilo taken by the mother only 0.2 mg is secreted into breast milk. This amount would not be harmful for the child since the dose to a child as chemo-prophylaxis for malaria is 8 mg per kilo each week. Avoid using it in patients suffering G-6-P-dehydrogenasa. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Answer by DrLact: About Sopaquin usage in lactation

Very small amounts of Sopaquin are excreted in breast milk; when given once weekly, the amount of drug is not sufficient to harm the infant nor is the quantity sufficient to protect the child from malaria. United Kingdom malaria treatment guidelines recommend that weekly Sopaquin 500 mg be given until breastfeeding is completed and primaquine can be given.[1] Breastfeeding infants should receive the recommended dosages of Sopaquin for malaria prophylaxis.[2] In HIV-infected women, elevated viral HIV loads in milk were decreased after treatment with Sopaquin to a greater extent than other women who were treated with the combination of sulfadoxine and pyrimethamine.[3] Because no information is available on the daily use of Sopaquin during breastfeeding, hydroxySopaquin or another agent may be preferred in this situation, especially while nursing a newborn or preterm infant.

Sopaquin Side Effects in Breastfeeding

Several authors have pointed out that malaria prophylaxis in nursing mothers with Sopaquin is common in endemic areas.[7][8][9] As of the revision date, no reports of adverse reactions in breastfed infants have been published.

Alternate Drugs

Neomycin(Safe)
Primaquine(Low Risk)
Cefotetan(Safe)
Abacavir(Safe)
Enoxacin(Low Risk)
Nafcillin(Safe)
Doxycycline(Low Risk)
Nevirapine(Low Risk)
Tenofovir(Safe)
Moxifloxacin(Low Risk)
Nelfinavir(Unsafe)
Amikacin(Safe)
Naftifine(Safe)
Cefixime(Safe)
Demeclocycline(Low Risk)
Methicillin(Low Risk)
Famciclovir(Low Risk)
Cefepime(Safe)
Meropenem(Safe)
Atovaquone(Low Risk)
Erythromycin(Low Risk)
Saquinavir(Unsafe)
Linezolid(Low Risk)
Clindamycin(Low Risk)
Cefdinir(Safe)
Indinavir(Unsafe)
Lomefloxacin(Low Risk)
Cefazolin(Safe)
Valganciclovir(Low Risk)
Levofloxacin(Low Risk)
Ganciclovir(Low Risk)
Rifaximin(Safe)
Kanamycin(Safe)
Acyclovir(Safe)
Cefaclor(Safe)
Econazole(Safe)
Efavirenz(Unsafe)
Dapsone(Low Risk)
Malathion(Low Risk)
Didanosine(Unsafe)
Quinine(Safe)
Aztreonam(Safe)
Amantadine(Low Risk)
Cefprozil(Safe)
Lindane(Unsafe)
Capreomycin(Low Risk)
Ofloxacin(Safe)
Gatifloxacin(Low Risk)
Ertapenem(Safe)
Cefoxitin(Safe)
Ritonavir(Unsafe)
Zidovudine(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Pyrantel(Safe)
Atovaquone(Low Risk)
Malathion(Low Risk)
Quinine(Safe)
Lindane(Unsafe)
Primaquine(Low Risk)
Atovaquone(Low Risk)
Quinine(Safe)
Primaquine(Low Risk)
Methotrexate(Low Risk)
Tocilizumab(Low Risk)
Anakinra(Low Risk)
Penicillamine(Low Risk)
Abatacept(Low Risk)
Auranofin(Low Risk)
Rituximab(Low Risk)
Leflunomide(Dangerous)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.