Is Glipizide Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Glipizide? Is Glipizide safe for nursing mother and child? Does Glipizide extracts into breast milk? Does Glipizide has any long term or short term side effects on infants? Can Glipizide influence milk supply or can Glipizide decrease milk supply in lactating mothers?
Glipizide lactation summary
- DrLact safety Score for Glipizide is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Glipizide is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Glipizide does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Glipizide safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Glipizide usage in lactation
Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus
Answer by DrLact: About Glipizide usage in lactation
Limited data indicate that the levels of glipizide in milk are low. However, an alternate drug for which there is more information may be preferred, especially while nursing a newborn or preterm infant. Monitor breastfed infants for signs of hypoglycemia such as jitteriness, excessive sleepiness, poor feeding, seizures cyanosis, apnea, or hypothermia. If there is concern, monitoring of the breastfed infant's blood glucose is advisable during maternal therapy with hypoglycemic agents.[1][2]
Glipizide Side Effects in Breastfeeding
Blood glucose levels were normal in 2 breastfed infants whose mothers were taking oral glipizide 5 mg daily.[3]
Alternate Drugs
Insulin(Safe)
Alogliptin(Low Risk)
Glyburide(Safe)
Linagliptin(Low Risk)
Sitagliptin(Low Risk)
Saxagliptin(Low Risk)
Glipizide(Safe)
Colesevelam(Safe)
Miglitol(Safe)
Glimepiride(Unsafe)
Tolbutamide(Safe)
Dulaglutide(Low Risk)
Chlorpropamide(Low Risk)
Liraglutide(Low Risk)
Acetohexamide(Low Risk)
Rosiglitazone(Low Risk)
Acarbose(Safe)
Repaglinide(Unsafe)
Pioglitazone(Low Risk)
Nateglinide(Unsafe)
Empagliflozin(Unsafe)
Metformin(Safe)
Dapagliflozin(Unsafe)
Glyburide(Safe)
Glipizide(Safe)
Glimepiride(Unsafe)
Tolbutamide(Safe)
Chlorpropamide(Low Risk)
Acetohexamide(Low Risk)