Question

I am a breastfeeding mother and i want to know if it is safe to use Epinastinum? Is Epinastinum safe for nursing mother and child? Does Epinastinum extracts into breast milk? Does Epinastinum has any long term or short term side effects on infants? Can Epinastinum influence milk supply or can Epinastinum decrease milk supply in lactating mothers?

Epinastinum lactation summary

Epinastinum usage has low risk in breastfeeding
  • DrLact safety Score for Epinastinum is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Epinastinum may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Epinastinum may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Epinastinum low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Epinastinum We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Epinastinum usage in lactation

It is a not sedative anti-histaminic (second generation) drug without an anti-muscarinic activity.

Answer by DrLact: About Epinastinum usage in lactation

Because absorption from the eye is limited, Epinastinum would not be expected to cause any adverse effects in breastfed infants. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Epinastinum Side Effects in Breastfeeding

There are no reports of infants breastfed during maternal therapy with Epinastinum. In one telephone follow-up study, mothers reported irritability and colicky symptoms in 10% of infants exposed to various antihistamines and drowsiness was reported in 1.6% of infants. None of the reactions required medical attention.[1]

Epinastinum Possible Effects in Breastfeeding

Antihistamines in relatively high doses given by injection can decrease basal serum prolactin in nonlactating women and in early postpartum women.[2][3] However, suckling-induced prolactin secretion is not affected by antihistamine pretreatment of postpartum mothers.[2] The prolactin level in a mother with established lactation may not affect her ability to breastfeed. Low ophthalmic doses of Epinastinum are unlikely to have the same effect on serum prolactin.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.