Is (+-)-Esmolol Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (+-)-Esmolol? Is (+-)-Esmolol safe for nursing mother and child? Does (+-)-Esmolol extracts into breast milk? Does (+-)-Esmolol has any long term or short term side effects on infants? Can (+-)-Esmolol influence milk supply or can (+-)-Esmolol decrease milk supply in lactating mothers?
Answer by DrLact: About (+-)-Esmolol usage in lactation
Based on its physicochemical properties and extremely short half-life, (+-)-Esmolol would not be expected to cause any adverse effects in breastfed infants.
(+-)-Esmolol Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking (+-)-Esmolol.[2]
(+-)-Esmolol Possible Effects in Breastfeeding
Relevant published information on the effects of beta-blockade or (+-)-Esmolol during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[3]
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