Is Sunitinib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Sunitinib? Is Sunitinib safe for nursing mother and child? Does Sunitinib extracts into breast milk? Does Sunitinib has any long term or short term side effects on infants? Can Sunitinib influence milk supply or can Sunitinib decrease milk supply in lactating mothers?
Answer by DrLact: About Sunitinib usage in lactation
No information is available on the clinical use of sunitinib during breastfeeding. Because sunitinib and its metabolite are over 90% bound to plasma proteins, the amount in milk is likely to be low. However, one of its metabolites has a half-life of up to 110 hours, and might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during sunitinib therapy and for at least 4 weeks after the last dose.
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