Is Vismodegib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Vismodegib? Is Vismodegib safe for nursing mother and child? Does Vismodegib extracts into breast milk? Does Vismodegib has any long term or short term side effects on infants? Can Vismodegib influence milk supply or can Vismodegib decrease milk supply in lactating mothers?
Answer by DrLact: About Vismodegib usage in lactation
No information is available on the clinical use of vismodegib during breastfeeding. Because vismodegib is more than 99% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is 4 days and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during vismodegib therapy and for 24 months after the final dose.
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