Question

I am a breastfeeding mother and i want to know if it is safe to use Levobunololum? Is Levobunololum safe for nursing mother and child? Does Levobunololum extracts into breast milk? Does Levobunololum has any long term or short term side effects on infants? Can Levobunololum influence milk supply or can Levobunololum decrease milk supply in lactating mothers?

Levobunololum lactation summary

Levobunololum usage has low risk in breastfeeding
  • DrLact safety Score for Levobunololum is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Levobunololum may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Levobunololum may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Levobunololum low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Levobunololum We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Levobunololum usage in lactation

Systemic absorption is minimal. There have not been problems except when a maternal overdose has been absorbed. Like most ophthalmologic compounds for topical use a low dose and poor absorption make it compatible with breastfeeding.

Answer by DrLact: About Levobunololum usage in lactation

Based on its physicochemical properties and its ophthalmic route of administration, Levobunololum appears to present a moderately low risk to the breastfed infant. To substantially diminish the amount of drug that reaches the breastmilk after using eye drops, place pressure over the tear duct by the corner of the eye for 1 minute or more, then remove the excess solution with an absorbent tissue.

Levobunololum Side Effects in Breastfeeding

A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking Levobunololum.[2]

Levobunololum Possible Effects in Breastfeeding

Relevant published information on the effects of beta-blockade or Levobunololum during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[3]

Alternate Drugs

Sotalol(Low Risk)
Bisoprolol(Low Risk)
Carteolol(Unsafe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Nadolol(Unsafe)
Nebivolol(Unsafe)
Timolol(Safe)
Carvedilol(Low Risk)
Amiodarone(Unsafe)
Sotalol(Low Risk)
Bisoprolol(Low Risk)
Diltiazem(Safe)
Quinidine(Safe)
Digoxin(Safe)
Levobunolol(Low Risk)
Atenolol(Unsafe)
Propafenone(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Lidocaine(Safe)
Nadolol(Unsafe)
Verapamil(Safe)
Timolol(Safe)
Brinzolamide(Low Risk)
Pilocarpine(Unsafe)
Carteolol(Unsafe)
Levobunolol(Low Risk)
Phenylephrine(Low Risk)
Timolol(Safe)
Amlodipine(Low Risk)
Valsartan(Low Risk)
Trandolapril(Dangerous)
Timolol(Safe)
Carvedilol(Low Risk)
Torsemide(Low Risk)
Enalapril(Safe)
Minoxidil(Safe)
Terazosin(Unsafe)
Sotalol(Low Risk)
Bisoprolol(Low Risk)
Telmisartan(Unsafe)
Reserpine(Unsafe)
Prazosin(Unsafe)
Ramipril(Low Risk)
Diltiazem(Safe)
Guanfacine(Low Risk)
Lisinopril(Low Risk)
Isradipine(Low Risk)
Chlorthalidone(Dangerous)
Indapamide(Low Risk)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Losartan(Low Risk)
Captopril(Safe)
Bosentan(Low Risk)
Bumetanide(Low Risk)
Irbesartan(Unsafe)
Acebutolol(Unsafe)
Furosemide(Low Risk)
Labetalol(Safe)
Nebivolol(Unsafe)
Fosinopril(Low Risk)
Eprosartan(Low Risk)
Nisoldipine(Low Risk)
Nadolol(Unsafe)
Verapamil(Safe)
Felodipine(Low Risk)
Doxazosin(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.