Is 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol? Is 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol safe for nursing mother and child? Does 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol extracts into breast milk? Does 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol has any long term or short term side effects on infants? Can 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol influence milk supply or can 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol decrease milk supply in lactating mothers?
Answer by DrLact: About 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol usage in lactation
Recommendation for Use During Lactation: Limited information indicates that maternal 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol produces low levels in milk. It also has a short half-life and only moderate renal excretion, so it would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.
1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol Side Effects in Breastfeeding
Relevant published information on 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol was not found as of the revision date. A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol.[3]
1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol Possible Effects in Breastfeeding
Relevant published information on the effects of beta-blockade or 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[4]
Alternate Drugs
Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nebivolol(Unsafe)
Nadolol(Unsafe)
Carvedilol(Low Risk)
Timolol(Safe)
Metoprolol(Safe)
Bisoprolol(Low Risk)
Sotalol(Low Risk)
Propranolol(Safe)
Atenolol(Unsafe)
Procainamide(Safe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Flecainide(Safe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
Lidocaine(Safe)
Timolol(Safe)
Mexiletine(Safe)
Metoprolol(Safe)
Disopyramide(Safe)
Bisoprolol(Low Risk)
Diltiazem(Safe)
Sotalol(Low Risk)
Digoxin(Safe)
Quinidine(Safe)
Propranolol(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Propafenone(Low Risk)
Propranolol(Safe)
Captopril(Safe)
Atenolol(Unsafe)
Eprosartan(Low Risk)
Hydrochlorothiazide(Safe)
Levobunolol(Low Risk)
Bumetanide(Low Risk)
Doxazosin(Safe)
Hydralazine(Safe)
Bosentan(Low Risk)
Nitrendipine(Safe)
Acebutolol(Unsafe)
Guanfacine(Low Risk)
Furosemide(Low Risk)
Labetalol(Safe)
Nisoldipine(Low Risk)
Bendroflumethiazide(Unsafe)
Fosinopril(Low Risk)
Nebivolol(Unsafe)
Nimodipine(Safe)
Benazepril(Safe)
Verapamil(Safe)
Nifedipine(Safe)
Amlodipine(Low Risk)
Nicardipine(Safe)
Felodipine(Low Risk)
Trandolapril(Dangerous)
Valsartan(Low Risk)
Minoxidil(Safe)
Nadolol(Unsafe)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Terazosin(Unsafe)
Telmisartan(Unsafe)
Spironolactone(Safe)
Timolol(Safe)
Prazosin(Unsafe)
Methyldopa(Safe)
Metoprolol(Safe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Ramipril(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Sotalol(Low Risk)
Isradipine(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Indapamide(Low Risk)
Chlorothiazide(Safe)