Question

I am a breastfeeding mother and i want to know if it is safe to use Pynastin? Is Pynastin safe for nursing mother and child? Does Pynastin extracts into breast milk? Does Pynastin has any long term or short term side effects on infants? Can Pynastin influence milk supply or can Pynastin decrease milk supply in lactating mothers?

Answer by DrLact: About Pynastin usage in lactation

Recommendation for Use During Lactation: Limited information indicates that maternal Pynastin produces low levels in milk. It also has a short half-life and only moderate renal excretion, so it would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months.

Pynastin Side Effects in Breastfeeding

Relevant published information on Pynastin was not found as of the revision date. A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. None of the mothers were taking Pynastin.[3]

Pynastin Possible Effects in Breastfeeding

Relevant published information on the effects of beta-blockade or Pynastin during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[4]

Alternate Drugs

Levobunolol(Low Risk)
Acebutolol(Unsafe)
Labetalol(Safe)
Carteolol(Unsafe)
Nebivolol(Unsafe)
Nadolol(Unsafe)
Carvedilol(Low Risk)
Timolol(Safe)
Bisoprolol(Low Risk)
Sotalol(Low Risk)
Atenolol(Unsafe)
Acebutolol(Unsafe)
Labetalol(Safe)
Verapamil(Safe)
Nadolol(Unsafe)
Amiodarone(Unsafe)
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Bisoprolol(Low Risk)
Diltiazem(Safe)
Sotalol(Low Risk)
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Quinidine(Safe)
Atenolol(Unsafe)
Levobunolol(Low Risk)
Propafenone(Low Risk)
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Atenolol(Unsafe)
Eprosartan(Low Risk)
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Bumetanide(Low Risk)
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Bosentan(Low Risk)
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Verapamil(Safe)
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Nadolol(Unsafe)
Torsemide(Low Risk)
Enalapril(Safe)
Carvedilol(Low Risk)
Terazosin(Unsafe)
Telmisartan(Unsafe)
Timolol(Safe)
Prazosin(Unsafe)
Reserpine(Unsafe)
Diltiazem(Safe)
Bisoprolol(Low Risk)
Ramipril(Low Risk)
Losartan(Low Risk)
Lisinopril(Low Risk)
Sotalol(Low Risk)
Isradipine(Low Risk)
Chlorthalidone(Dangerous)
Irbesartan(Unsafe)
Indapamide(Low Risk)
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