Question

I am a breastfeeding mother and i want to know if it is safe to use Teicoplanin? Is Teicoplanin safe for nursing mother and child? Does Teicoplanin extracts into breast milk? Does Teicoplanin has any long term or short term side effects on infants? Can Teicoplanin influence milk supply or can Teicoplanin decrease milk supply in lactating mothers?

Teicoplanin lactation summary

Teicoplanin is safe in breastfeeding
  • DrLact safety Score for Teicoplanin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Teicoplanin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Teicoplanin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Teicoplanin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Teicoplanin usage in lactation

Antibacterial glycopeptide, administered via intravenous or intramuscularinjection. Its pharmacokinetic data (high molecular weight, high percentage of plasma protein binding and no oral bioavailability) explain the negligible passage into milk observed (Fraissinet 2017) and the absence of side effects in a 52-day-old infant whose mother was being treated with teicoplanin (Kaplan 2017). Not being absorbed orally, there would be no passage to the infant's plasma from ingested breast milk. It is an antibiotic that is administered, if necessary, to newborns. The possible negativity of cultures in febrile infants whose mothers take antibiotics should be taken into account, as well as the possibility of gastroenteritis due to altered intestinal flora.

Answer by DrLact: About Teicoplanin usage in lactation

Teicoplanin is not approved for marketing in the United States by the U.S. Food and Drug Administration, but is available in other countries. Limited data indicate that teicoplanin is poorly excreted into breastmilk. Because teicoplanin is not orally absorbed it is unlikely to adversely affect the breastfed infant. One infant was safely breastfed during maternal therapy with teicoplanin and ceftriaxone. Until more information becomes available, monitor the breastfed infant for gastrointestinal disturbances such as diarrhea, particularly in newborn and preterm infants.

Teicoplanin Side Effects in Breastfeeding

A mother who was exclusively nursing her 52-day-old infant developed a soft-tissue infection. She was treated with intravenous teicoplanin 400 mg every 12 hours for 3 doses, then 400 mg daily for 5 days total, intravenous ceftriaxone 1 gram daily, and topical mupirocin cream twice daily. A careful follow-up indicated that her infant had no adverse effects.[2]

Alternate Drugs

Zidovudine(Low Risk)
Ganciclovir(Low Risk)
Cefepime(Safe)
Amantadine(Low Risk)
Moxifloxacin(Low Risk)
Clindamycin(Low Risk)
Econazole(Safe)
Tenofovir(Safe)
Aztreonam(Safe)
Cefprozil(Safe)
Lindane(Unsafe)
Acyclovir(Safe)
Cefdinir(Safe)
Quinine(Safe)
Primaquine(Low Risk)
Efavirenz(Unsafe)
Saquinavir(Unsafe)
Methicillin(Low Risk)
Atovaquone(Low Risk)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Didanosine(Unsafe)
Cefoxitin(Safe)
Linezolid(Low Risk)
Ofloxacin(Safe)
Malathion(Low Risk)
Enoxacin(Low Risk)
Cefotetan(Safe)
Ritonavir(Unsafe)
Meropenem(Safe)
Naftifine(Safe)
Cefaclor(Safe)
Doxycycline(Low Risk)
Abacavir(Safe)
Nevirapine(Low Risk)
Dapsone(Low Risk)
Nelfinavir(Unsafe)
Amikacin(Safe)
Neomycin(Safe)
Lomefloxacin(Low Risk)
Capreomycin(Low Risk)
Famciclovir(Low Risk)
Rifaximin(Safe)
Levofloxacin(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Ertapenem(Safe)
Nafcillin(Safe)
Erythromycin(Low Risk)
Valganciclovir(Low Risk)
Kanamycin(Safe)
Indinavir(Unsafe)
Moxifloxacin(Low Risk)
Clindamycin(Low Risk)
Aztreonam(Safe)
Cefprozil(Safe)
Cefdinir(Safe)
Methicillin(Low Risk)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Ofloxacin(Safe)
Methenamine(Unsafe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Cefaclor(Safe)
Doxycycline(Low Risk)
Mupirocin(Safe)
Neomycin(Safe)
Lomefloxacin(Low Risk)
Capreomycin(Low Risk)
Amikacin(Safe)
Nalidixic Acid(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Levofloxacin(Low Risk)
Ertapenem(Safe)
Nafcillin(Safe)
Erythromycin(Low Risk)
Iodine(Unsafe)
Kanamycin(Safe)
Cefepime(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.