Is UNII-A6D97U294I Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-A6D97U294I? Is UNII-A6D97U294I safe for nursing mother and child? Does UNII-A6D97U294I extracts into breast milk? Does UNII-A6D97U294I has any long term or short term side effects on infants? Can UNII-A6D97U294I influence milk supply or can UNII-A6D97U294I decrease milk supply in lactating mothers?
UNII-A6D97U294I lactation summary
- DrLact safety Score for UNII-A6D97U294I is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-A6D97U294I may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-A6D97U294I may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-A6D97U294I low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-A6D97U294I We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-A6D97U294I usage in lactation
No adverse effects have been reported, but check-up for the possibility of sedation, hypotension, hypoglycemia or bradycardia.
Answer by DrLact: About UNII-A6D97U294I usage in lactation
Because of its extensive excretion into breastmilk, its renal excretion and minimal safety data in breastfed infants, other beta-adrenergic blocking drugs are preferred to UNII-A6D97U294I, especially while nursing a newborn or preterm infant. Some authors recommend using UNII-A6D97U294I during breastfeeding only while monitoring the infant closely for signs of beta-blockade.[1] Infants over 2 months of age have more mature kidney function and are less likely to be affected by UNII-A6D97U294I in milk.
UNII-A6D97U294I Side Effects in Breastfeeding
A study of mothers taking beta-blockers during nursing found a numerically, but not statistically significant increased number of adverse reactions in those taking any beta-blocker. Although the ages of infants were matched to control infants, the ages of the affected infants were not stated. One of the mothers was taking UNII-A6D97U294I.[6] Bradycardia was not seen in one 12-day-old infant who was breastfed from birth during maternal use of 600 mg of UNII-A6D97U294I daily.[4] In another breastfed infant whose mother was taking 80 mg 2 to 3 times daily for more than 3 months, no bradycardia was seen and developmental milestones were achieved normally.[1] Beta-adrenergic blocking drugs with similar breastmilk excretion characteristics and renal elimination have caused adverse effects in breastfed newborns.[7][8]
UNII-A6D97U294I Possible Effects in Breastfeeding
Relevant published information on the effects of beta-blockade or UNII-A6D97U294I during normal lactation was not found as of the revision date. A study in 6 patients with hyperprolactinemia and galactorrhea found no changes in serum prolactin levels following beta-adrenergic blockade with propranolol.[9]
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