Is Midostaurin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Midostaurin? Is Midostaurin safe for nursing mother and child? Does Midostaurin extracts into breast milk? Does Midostaurin has any long term or short term side effects on infants? Can Midostaurin influence milk supply or can Midostaurin decrease milk supply in lactating mothers?
Answer by DrLact: About Midostaurin usage in lactation
No information is available on the clinical use of midostaurin during breastfeeding. Because midostaurin and its active metabolites are 99.8% bound to plasma proteins, the amount in milk is likely to be low. The manufacturer recommends that breastfeeding be discontinued during midostaurin therapy and for at least 4 months after the last dose. Avoiding breastfeeding is particularly important when midostaurin is given with other cancer chemotherapy agents.
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