I am a breastfeeding mother and i want to know if it is safe to use Sugammadex? Is Sugammadex safe for nursing mother and child? Does Sugammadex extracts into breast milk? Does Sugammadex has any long term or short term side effects on infants? Can Sugammadex influence milk supply or can Sugammadex decrease milk supply in lactating mothers?

Sugammadex lactation summary

Sugammadex is safe in breastfeeding
  • DrLact safety Score for Sugammadex is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Sugammadex is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Sugammadex does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Sugammadex safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Sugammadex usage in lactation

A modified gamma-cyclodextrin that binds to rocuronium or vecuronium, reversing its neuromuscular blocking action. Used intravenously. Since the last update we have not found published data on its excretion in breast milk. Side effects are rare and mild.It is administered in single or isolated doses. Its high molecular weight makes it unlikely that it will pass into milk in significant amounts. Its low oral bioavailability would make it difficult its passage to the infant’s plasma through breast milk (EMA 2017).Sugammadex can be used during breastfeeding (EMA 2017)

Answer by DrLact: About Sugammadex usage in lactation

No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002, the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1]

Alternate Drugs

Synonyms of Sugammadex

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.