Question

I am a breastfeeding mother and i want to know if it is safe to use Carmustine? Is Carmustine safe for nursing mother and child? Does Carmustine extracts into breast milk? Does Carmustine has any long term or short term side effects on infants? Can Carmustine influence milk supply or can Carmustine decrease milk supply in lactating mothers?

Carmustine lactation summary

Carmustine is dangerous in breastfeeding
  • DrLact safety Score for Carmustine is 7 out of 8 which is considered Dangerous as per our analyses.
  • A safety Score of 7 indicates that usage of Carmustine may cause toxic or severe side effects in breastfed baby.
  • Our study of different scientific research indicates that Carmustine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Carmustine .
  • Usage of Carmustine is in contradiction to breastfeeding hence if it is must to use Carmustine and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Carmustine usage in lactation

Drug is cleared from the body after 25-50 elimination half-life. Resuming breastfeeding is likely safe after 48 hours of pump-and-dump.

Answer by DrLact: About Carmustine usage in lactation

No information is available on the use of carmustine during breastfeeding. Most sources consider breastfeeding to be contraindicated during maternal antineoplastic drug therapy, especially alkylating agents such as carmustine.[1] The manufacturer recommends that breastfeeding be discontinued during carmustine therapy and for 1 month after the last dose.

Carmustine Possible Effects in Breastfeeding

Some evidence indicates that carmustine can increase serum prolactin.[2]

Alternate Drugs

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.