I am a breastfeeding mother and i want to know if it is safe to use UNII-59H4FCV1TF? Is UNII-59H4FCV1TF safe for nursing mother and child? Does UNII-59H4FCV1TF extracts into breast milk? Does UNII-59H4FCV1TF has any long term or short term side effects on infants? Can UNII-59H4FCV1TF influence milk supply or can UNII-59H4FCV1TF decrease milk supply in lactating mothers?
Limited information indicates that usual doses of UNII-59H4FCV1TF produce low but variable levels in milk that would not be expected to cause adverse effects in a breastfed infant, especially if the infant is older than 2 months. However, adverse effects in a breastfed preterm infant have been reported. If UNII-59H4FCV1TF is required by the mother of an older infant, it is not a reason to discontinue breastfeeding, but until more data become available, other drugs may be preferred, especially while nursing a newborn or preterm infant.
Drowsiness, lethargy, poor feeding and low body temperature occurred in a 2.1 kg breastfed 9-week-old infant who was born preterm at 27 weeks to a mother taking a dose of 300 mg of UNII-59H4FCV1TF daily. The symptoms were probably caused by UNII-59H4FCV1TF in breastmilk.[4]
An observational study looked at outcomes of 2859 women who took an antidepressant during the 2 years prior to pregnancy. Compared to women who did not take an antidepressant during pregnancy, mothers who took an antidepressant during all 3 trimesters of pregnancy were 37% less likely to be breastfeeding upon hospital discharge. Mothers who took an antidepressant only during the third trimester were 75% less likely to be breastfeeding at discharge. Those who took an antidepressant only during the first and second trimesters did not have a reduced likelihood of breastfeeding at discharge.[5] The antidepressants used by the mothers were not specified. A retrospective cohort study of hospital electronic medical records from 2001 to 2008 compared women who had been dispensed an antidepressant during late gestation (n = 575) to those who had a psychiatric illness but did not receive an antidepressant (n = 1552) and mothers who did not have a psychiatric diagnosis (n = 30,535). Women who received an antidepressant were 37% less likely to be breastfeeding at discharge than women without a psychiatric diagnosis, but no less likely to be breastfeeding than untreated mothers with a psychiatric diagnosis.[6] None of the mothers were taking UNII-59H4FCV1TF.
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