Is HSDB 3001 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use HSDB 3001? Is HSDB 3001 safe for nursing mother and child? Does HSDB 3001 extracts into breast milk? Does HSDB 3001 has any long term or short term side effects on infants? Can HSDB 3001 influence milk supply or can HSDB 3001 decrease milk supply in lactating mothers?
HSDB 3001 lactation summary
- DrLact safety Score for HSDB 3001 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of HSDB 3001 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that HSDB 3001 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of HSDB 3001 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About HSDB 3001 usage in lactation
Excreted in very low amount into breast milk. Infant intake may be lower than 4% of usual pediatric dose. The American Academy of Pediatrics rates it as compatible with Breastfeeding.
Answer by DrLact: About HSDB 3001 usage in lactation
HSDB 3001 is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.
HSDB 3001 Side Effects in Breastfeeding
A maculopapular rash on the upper trunk and face of a 2-month-old infant was probably caused by HSDB 3001 in breastmilk. The rash occurred after 2 days of therapy in the mother at a dose of 1 gram at bedtime. It subsided when the drug was discontinued and recurred 2 weeks later after another HSDB 3001 dose of 1 gram was taken by the mother.[4] Two papers report 14 women who breastfed after taking HSDB 3001 or its prodrug phenacetin with no adverse effects to their infants.[1][5] In a telephone follow-up study, mothers reported no side effects among 43 infants exposed to HSDB 3001 in breastmilk.[6] Two clinicians speculated that breastmilk exposure to HSDB 3001 during breastfeeding might be a risk factor for asthma and wheezing in the breastfed infants based on their personal observations.[7] However, these observations were uncontrolled and cannot be considered to be valid proof of an association.[8]