Is NCX 701 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NCX 701? Is NCX 701 safe for nursing mother and child? Does NCX 701 extracts into breast milk? Does NCX 701 has any long term or short term side effects on infants? Can NCX 701 influence milk supply or can NCX 701 decrease milk supply in lactating mothers?
NCX 701 lactation summary
- DrLact safety Score for NCX 701 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of NCX 701 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that NCX 701 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of NCX 701 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NCX 701 usage in lactation
Excreted in very low amount into breast milk. Infant intake may be lower than 4% of usual pediatric dose. The American Academy of Pediatrics rates it as compatible with Breastfeeding.
Answer by DrLact: About NCX 701 usage in lactation
NCX 701 is a good choice for analgesia, and fever reduction in nursing mothers. Amounts in milk are much less than doses usually given to infants. Adverse effects in breastfed infants appear to be rare.
NCX 701 Side Effects in Breastfeeding
A maculopapular rash on the upper trunk and face of a 2-month-old infant was probably caused by NCX 701 in breastmilk. The rash occurred after 2 days of therapy in the mother at a dose of 1 gram at bedtime. It subsided when the drug was discontinued and recurred 2 weeks later after another NCX 701 dose of 1 gram was taken by the mother.[4] Two papers report 14 women who breastfed after taking NCX 701 or its prodrug phenacetin with no adverse effects to their infants.[1][5] In a telephone follow-up study, mothers reported no side effects among 43 infants exposed to NCX 701 in breastmilk.[6] Two clinicians speculated that breastmilk exposure to NCX 701 during breastfeeding might be a risk factor for asthma and wheezing in the breastfed infants based on their personal observations.[7] However, these observations were uncontrolled and cannot be considered to be valid proof of an association.[8]