Question

I am a breastfeeding mother and i want to know if it is safe to use Lutetium Lu 177 Dotatate? Is Lutetium Lu 177 Dotatate safe for nursing mother and child? Does Lutetium Lu 177 Dotatate extracts into breast milk? Does Lutetium Lu 177 Dotatate has any long term or short term side effects on infants? Can Lutetium Lu 177 Dotatate influence milk supply or can Lutetium Lu 177 Dotatate decrease milk supply in lactating mothers?

Answer by DrLact: About Lutetium Lu 177 Dotatate usage in lactation

Lutetium Lu 177 dotatate is a radiolabeled somatostatin analog indicated for the treatment of somatostatin receptor-positive gastroenteropancreatic neuroendocrine tumors. No information is available on the use of lutetium Lu 177 dotatate during breastfeeding. The manufacturer recommends that breastfeeding be discontinued during lutetium Lu 177 dotatate therapy and for 2.5 months following the last dose, which would usually mean permanently discontinuing breastfeeding of the current infant. Mothers concerned about the level of radioactivity in their milk could ask to have it tested at a nuclear medicine facility at their hospital. When the radioactivity is at a safe level she may resume breastfeeding. A method for measuring milk radioactivity and determining the time when a mother can safely resume breastfeeding has been published.[1]

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