Is Tildrakizumab Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Tildrakizumab? Is Tildrakizumab safe for nursing mother and child? Does Tildrakizumab extracts into breast milk? Does Tildrakizumab has any long term or short term side effects on infants? Can Tildrakizumab influence milk supply or can Tildrakizumab decrease milk supply in lactating mothers?

No information is available on the clinical use of tildrakizumab during breastfeeding. Because tildrakizumab is a large protein molecule with a molecular weight of 147,000, absorption by the infant is unlikely after the first few weeks postpartum, and it will probably be destroyed in the infant's gastrointestinal tract. Until more data become available, tildrakizumab should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. Tildrakizumab is a human immunoglobulin G1 (IgG1) kappa antibody. Holder pasteurization (62.5 degrees C for 30 minutes) decreases the concentration of endogenous immunoglobulin G by up to 79%.[1][2] A study of 67 colostrum samples that underwent Holder pasteurization found that IgG amounts decreased by 34 to 40%. Specific IgG subclasses decreased by different amounts, with IgG1 activity decreasing by about 37%.[3] None of the studies measured IgG activity.