Question

I am a breastfeeding mother and i want to know if it is safe to use Lofexidine? Is Lofexidine safe for nursing mother and child? Does Lofexidine extracts into breast milk? Does Lofexidine has any long term or short term side effects on infants? Can Lofexidine influence milk supply or can Lofexidine decrease milk supply in lactating mothers?

Answer by DrLact: About Lofexidine usage in lactation

No information is available on the use of lofexidine during breastfeeding. Lofexidine is chemically and pharmacologically related to clonidine, which reaches high levels in milk and in the breastfed infant. Although it is not contraindicated during breastfeeding, lofexidine should be used with caution during breastfeeding, especially while nursing a newborn or preterm infant. An alternate drug may be preferred, especially while nursing a newborn or preterm infant.

Alternate Drugs

Lofexidine
Lofexidine
Naloxone(Low Risk)
Pentazocine(Low Risk)
Naltrexone(Low Risk)
Nalbuphine
Butorphanol(Low Risk)
Buprenorphine(Safe)

Synonyms of Lofexidine

2-(1-(2,6-Dichlorophenoxy)ethyl)-4,5-dihydro-1H-imidazole
2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazoline
Lofexidina [INN-Spanish]
Lofexidinum [INN-Latin]
Lofexidina
Lofexidinum
UNII-UI82K0T627
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