Is Ivosidenib Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Ivosidenib? Is Ivosidenib safe for nursing mother and child? Does Ivosidenib extracts into breast milk? Does Ivosidenib has any long term or short term side effects on infants? Can Ivosidenib influence milk supply or can Ivosidenib decrease milk supply in lactating mothers?
Answer by DrLact: About Ivosidenib usage in lactation
No information is available on the clinical use of ivosidenib during breastfeeding. Because ivosidenib is 92 to 96% bound to plasma proteins, the amount in milk is likely to be low. However, its half-life is about 93 hours and it might accumulate in the infant. The manufacturer recommends that breastfeeding be discontinued during erlotinib therapy and for 1 month after the dose.
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