Question

I am a breastfeeding mother and i want to know if it is safe to use Ampicillin and Sulbactam? Is Ampicillin and Sulbactam safe for nursing mother and child? Does Ampicillin and Sulbactam extracts into breast milk? Does Ampicillin and Sulbactam has any long term or short term side effects on infants? Can Ampicillin and Sulbactam influence milk supply or can Ampicillin and Sulbactam decrease milk supply in lactating mothers?

Answer by DrLact: About Ampicillin and Sulbactam usage in lactation

Limited information indicates that ampicillin-sulbactam produces low levels in milk that are not expected to cause adverse effects in breastfed infants. Occasionally, disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, have been reported with penicillins, but these effects have not been adequately evaluated. Ampicillin-sulbactam is acceptable in nursing mothers.

Ampicillin and Sulbactam Side Effects in Breastfeeding

Relevant published information on ampicillin and sulbactam was not found as of the revision date; however, there are data on ampicillin alone. In a prospective follow-up study, 5 nursing mothers reported taking oral ampicillin (dosage unspecified). One mother reported diarrhea in her infant. No rashes or candidiasis were reported among the exposed infants.[6] A small, controlled, prospective study had mothers monitor their infants for signs of adverse effects (furring of the tongue, feeding difficulties, changes in stool frequency and consistency, diaper rash, and skin rash). Weight change and the development of jaundice were also recorded. No statistical differences in these parameters were found between the infants of the control mothers and those of mothers taking oral ampicillin.[7]

Alternate Drugs

Nafcillin(Safe)
Atovaquone(Low Risk)
Levofloxacin(Low Risk)
Ritonavir(Unsafe)
Demeclocycline(Low Risk)
Linezolid(Low Risk)
Malathion(Low Risk)
Moxifloxacin(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Nevirapine(Low Risk)
Naftifine(Safe)
Abacavir(Safe)
Nelfinavir(Unsafe)
Dapsone(Low Risk)
Cefepime(Safe)
Capreomycin(Low Risk)
Famciclovir(Low Risk)
Amikacin(Safe)
Cefprozil(Safe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Rifaximin(Safe)
Indinavir(Unsafe)
Ertapenem(Safe)
Cefdinir(Safe)
Aztreonam(Safe)
Zidovudine(Low Risk)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Meropenem(Safe)
Cefazolin(Safe)
Enoxacin(Low Risk)
Econazole(Safe)
Cefoxitin(Safe)
Amantadine(Low Risk)
Tenofovir(Safe)
Lindane(Unsafe)
Neomycin(Safe)
Acyclovir(Safe)
Valganciclovir(Low Risk)
Doxycycline(Low Risk)
Cefotetan(Safe)
Quinine(Safe)
Ganciclovir(Low Risk)
Saquinavir(Unsafe)
Cefaclor(Safe)
Efavirenz(Unsafe)
Lomefloxacin(Low Risk)
Primaquine(Low Risk)
Didanosine(Unsafe)
Demeclocycline(Low Risk)
Moxifloxacin(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Cefepime(Safe)
Mupirocin(Safe)
Capreomycin(Low Risk)
Cefprozil(Safe)
Methicillin(Low Risk)
Ofloxacin(Safe)
Erythromycin(Low Risk)
Ertapenem(Safe)
Cefdinir(Safe)
Iodine(Unsafe)
Amikacin(Safe)
Methenamine(Unsafe)
Aztreonam(Safe)
Clindamycin(Low Risk)
Gatifloxacin(Low Risk)
Cefazolin(Safe)
Enoxacin(Low Risk)
Cefoxitin(Safe)
Neomycin(Safe)
Doxycycline(Low Risk)
Cefotetan(Safe)
Nalidixic Acid(Low Risk)
Cefaclor(Safe)
Lomefloxacin(Low Risk)
Nafcillin(Safe)
Levofloxacin(Low Risk)
Methicillin(Low Risk)
Nafcillin(Safe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.