Question

I am a breastfeeding mother and i want to know if it is safe to use Eravacycline? Is Eravacycline safe for nursing mother and child? Does Eravacycline extracts into breast milk? Does Eravacycline has any long term or short term side effects on infants? Can Eravacycline influence milk supply or can Eravacycline decrease milk supply in lactating mothers?

Answer by DrLact: About Eravacycline usage in lactation

No information is available on the use of eravacycline during breastfeeding. The manufacturer states that breastfeeding is not recommended during treatment and for 4 days after the last dose. However, based on the excretion of other tetracycline antibiotics and the high protein binding of eravacycline, amounts in milk are expected to be low and probably poorly absorbed orally by the breastfed infant. If an infant is breastfed, monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis. As a theoretical precaution, avoid prolonged or repeat courses during nursing.

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