Is Pemetrexed Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Pemetrexed? Is Pemetrexed safe for nursing mother and child? Does Pemetrexed extracts into breast milk? Does Pemetrexed has any long term or short term side effects on infants? Can Pemetrexed influence milk supply or can Pemetrexed decrease milk supply in lactating mothers?
Answer by DrLact: About Pemetrexed usage in lactation
Most sources consider breastfeeding to be contraindicated during maternal high-dose antineoplastic drug therapy. The manufacturer recommends that mothers should not to breastfeed during treatment with pemetrexed and for one week after the last dose. Chemotherapy may adversely affect the normal microbiome and chemical makeup of breastmilk.[1] Women who receive chemotherapy during pregnancy are more likely to have difficulty nursing their infant.[2]
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