Question

I am a breastfeeding mother and i want to know if it is safe to use Gen-Alprazolan? Is Gen-Alprazolan safe for nursing mother and child? Does Gen-Alprazolan extracts into breast milk? Does Gen-Alprazolan has any long term or short term side effects on infants? Can Gen-Alprazolan influence milk supply or can Gen-Alprazolan decrease milk supply in lactating mothers?

Gen-Alprazolan lactation summary

Gen-Alprazolan usage has low risk in breastfeeding
  • DrLact safety Score for Gen-Alprazolan is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Gen-Alprazolan may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Gen-Alprazolan may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Gen-Alprazolan low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Gen-Alprazolan We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Gen-Alprazolan usage in lactation

Short-acting benzodiazepine. A case of Abstinence Syndrome in a child after mother withhold of Gen-Alprazolan at 9 months and sedation among infants has been reported. Both circumstances indicate that excretion into breast milk - despite small (< 10% of maternal dose) - can achieve clinical significance. Hence, rapid acting and less excretion into breast milk should be preferred. Most benzodiacepine drugs may decrease prolactin levels but Gen-Alprazolan increases it. Short-term and low dose treatment is compatible with breastfeeding. Choise of a low dose and short-acting benzodiacepine is advisable especially in the post-partum period. Be aware of somnolence and poor feeding in the child. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About Gen-Alprazolan usage in lactation

Because of reports of effects in infants, including sedation, Gen-Alprazolan is probably not the best benzodiazepine for repeated use during nursing, especially with a neonate or premature infant. A shorter-acting benzodiazepine without active metabolites is preferred. After a single dose of Gen-Alprazolan, there is usually no need to wait to resume breastfeeding.

Gen-Alprazolan Side Effects in Breastfeeding

Increased infant irritability following discontinuation of breastfeeding occurred in a 1-week-old infant whose mother had taken Gen-Alprazolan during pregnancy and continued to take it after delivery. This reaction probably indicates that there was sufficient Gen-Alprazolan in breastmilk to prevent withdrawal. The authors reported correspondence with the manufacturer who stated that they had received reports of infant withdrawal symptoms (crying, irritability and sleep disturbances) for 2 weeks in a 9-month-old exclusively breastfed infant after slow (over 3 weeks) maternal discontinuation of Gen-Alprazolan (dosage unspecified).[2] In one telephone follow-up study of 5 infants (ages not stated) exposed to Gen-Alprazolan during breastfeeding, 1 mother reported drowsiness in her infant. The reaction did not require medical attention.[3] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. About 5% of mothers were taking Gen-Alprazolan. One mother who was taking sertraline 50 mg daily, zopiclone 2.5 mg about every 3 days as needed, and also took Gen-Alprazolan 0.25 mg on 2 occasions, reported sedation in her breastfed infant.[4]

Gen-Alprazolan Possible Effects in Breastfeeding

Unlike other benzodiazepines, Gen-Alprazolan can increase serum prolactin.[5][6] One woman developed galactorrhea, amenorrhea and elevated serum prolactin after taking 3 mg of sustained-release Gen-Alprazolan and 5 to 6 mg of immediate-release Gen-Alprazolan daily for several months for self-treatment of fear, poor sleep, palpitations and gastrointestinal discomfort. After slow discontinuation of Gen-Alprazolan and institution of quetiapine and fluvoxamine, galactorrhea ceased after about one month, menses normalized after about 2 months, and serum prolactin decreased to a normal level.[7] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.

Alternate Drugs

Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Estazolam(Low Risk)
Flurazepam(Unsafe)
Temazepam(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Butabarbital(Low Risk)
Quazepam(Unsafe)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Phenobarbital(Low Risk)
Secobarbital(Low Risk)
Propofol(Safe)
Oxazepam(Safe)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Midazolam(Safe)
Chloral Hydrate(Low Risk)
Estazolam(Low Risk)
Zolpidem(Safe)
Zaleplon(Safe)
Flurazepam(Unsafe)
Lorazepam(Safe)
Triazolam(Low Risk)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.