Question

I am a breastfeeding mother and i want to know if it is safe to use Amprenavir? Is Amprenavir safe for nursing mother and child? Does Amprenavir extracts into breast milk? Does Amprenavir has any long term or short term side effects on infants? Can Amprenavir influence milk supply or can Amprenavir decrease milk supply in lactating mothers?

Amprenavir lactation summary

Amprenavir is unsafe in breastfeeding
  • DrLact safety Score for Amprenavir is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Amprenavir may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Amprenavir may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Amprenavir .
  • It is recommended to evaluate the advantage of not breastfeeding while using Amprenavir Vs not using Amprenavir And continue breastfeeding.
  • While using Amprenavir Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Amprenavir usage in lactation

Anti-HIV drug. No experience in young infants. Withdrawn from market. Mothers should be aware of HIV transmission through breast milk has been reported.

Alternate Drugs for Antivirals for systemic use. ATC J05

Acyclovir(Safe)
Famciclovir(Low Risk)
Abacavir(Safe)
Didanosine(Unsafe)
Efavirenz(Unsafe)
Indinavir(Unsafe)
Nelfinavir(Unsafe)
Nevirapine(Low Risk)
Ritonavir(Unsafe)
Saquinavir(Unsafe)
Tenofovir(Safe)
Zidovudine(Low Risk)
Zanamivir(Safe)
Ribavirin(Low Risk)
Dasabuvir(Low Risk)
Daclatasvir(Low Risk)
Ombitasvir(Low Risk)
Ledipasvir(Low Risk)
Sofosbuvir(Low Risk)
Simeprevir(Low Risk)
Velpatasvir(Low Risk)
Ganciclovir(Low Risk)
Valganciclovir(Low Risk)
Brivudine(Low Risk)
Cidofovir(Unsafe)
Foscarnet(Unsafe)
Lysozyme(Safe)
Zalcitabine(Unsafe)
Tribavirin(Low Risk)
Azidothymidine(Low Risk)
Azt(Low Risk)
Aciclovir(Safe)
BW-248U(Safe)
Ddi(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.