Is Brivudine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Brivudine? Is Brivudine safe for nursing mother and child? Does Brivudine extracts into breast milk? Does Brivudine has any long term or short term side effects on infants? Can Brivudine influence milk supply or can Brivudine decrease milk supply in lactating mothers?
Brivudine lactation summary
- DrLact safety Score for Brivudine is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Brivudine may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Brivudine may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Brivudine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Brivudine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Brivudine usage in lactation
Medication used for treatment of Herpes zoster infection. At latest update, relevant published data on excretion into breast milk were not found. Because a high distribution volume (DV) and high protein-binding capacity, excretion into breast milk in significant amount is very unlikely. A low oral bioavailability impairs the pass of it from the mother's milk to the infant's plasma, except in prematures or in the early neonatal period, when a higher intestinal absorption may occur. Until more data on this medication is available, safer alternative drugs are preferred, especially in such critical age periods.
Alternate Drugs for Antivirals for systemic use. ATC J05
Acyclovir(Safe)
Famciclovir(Low Risk)
Oseltamivir(Safe)
Abacavir(Safe)
Didanosine(Unsafe)
Efavirenz(Unsafe)
Emtricitabine(Safe)
Indinavir(Unsafe)
Lamivudine(Safe)
Nelfinavir(Unsafe)
Nevirapine(Low Risk)
Ritonavir(Unsafe)
Saquinavir(Unsafe)
Tenofovir(Safe)
Zidovudine(Low Risk)
Zanamivir(Safe)
Ribavirin(Low Risk)
Dasabuvir(Low Risk)
Daclatasvir(Low Risk)
Ombitasvir(Low Risk)
Ledipasvir(Low Risk)
Sofosbuvir(Low Risk)
Simeprevir(Low Risk)
Velpatasvir(Low Risk)
Ganciclovir(Low Risk)
Valganciclovir(Low Risk)
Adefovir Dipivoxil(Unsafe)
Oseltamivir Phosphate(Safe)
Amprenavir(Unsafe)
Valaciclovir(Safe)
Cidofovir(Unsafe)
Foscarnet(Unsafe)
Lysozyme(Safe)
Rimantadine Hydrochloride(Low Risk)
Zalcitabine(Unsafe)
Tribavirin(Low Risk)
Globulin G1(Safe)
Azidothymidine(Low Risk)
Azt(Low Risk)
Muramidase(Safe)
Aciclovir(Safe)
BW-248U(Safe)
Ddi(Unsafe)
Acycloguanosine(Safe)