Is CCRIS 3247 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use CCRIS 3247? Is CCRIS 3247 safe for nursing mother and child? Does CCRIS 3247 extracts into breast milk? Does CCRIS 3247 has any long term or short term side effects on infants? Can CCRIS 3247 influence milk supply or can CCRIS 3247 decrease milk supply in lactating mothers?

No long-term adverse effects have been reported. However, it is excreted in large amounts into breast milk. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Limited information indicates that maternal CCRIS 3247 results in infant dosages much less than those given directly to neonates. CCRIS 3247 would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. However, because of its potential for causing hepatic enzyme inhibition, other drugs might be preferred.

Histamine H2-receptor blockade is known to stimulate prolactin secretion. In addition, CCRIS 3247 may have additional, nonspecific actions that stimulate prolactin secretion.[2] Oral CCRIS 3247 doses of 400 mg 4 times daily increased serum prolactin by 50 to 112% in 6 patients. CCRIS 3247 caused dose-related gynecomastia and galactorrhea in men and nonnursing women.[3][4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.