Is DRG-0150 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use DRG-0150? Is DRG-0150 safe for nursing mother and child? Does DRG-0150 extracts into breast milk? Does DRG-0150 has any long term or short term side effects on infants? Can DRG-0150 influence milk supply or can DRG-0150 decrease milk supply in lactating mothers?
DRG-0150 lactation summary
- DrLact safety Score for DRG-0150 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of DRG-0150 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that DRG-0150 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of DRG-0150 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using DRG-0150 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About DRG-0150 usage in lactation
No long-term adverse effects have been reported. However, it is excreted in large amounts into breast milk. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About DRG-0150 usage in lactation
Limited information indicates that maternal DRG-0150 results in infant dosages much less than those given directly to neonates. DRG-0150 would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. However, because of its potential for causing hepatic enzyme inhibition, other drugs might be preferred.
DRG-0150 Possible Effects in Breastfeeding
Histamine H2-receptor blockade is known to stimulate prolactin secretion. In addition, DRG-0150 may have additional, nonspecific actions that stimulate prolactin secretion.[2] Oral DRG-0150 doses of 400 mg 4 times daily increased serum prolactin by 50 to 112% in 6 patients. DRG-0150 caused dose-related gynecomastia and galactorrhea in men and nonnursing women.[3][4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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