Is UNII-80061L1WGD Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-80061L1WGD? Is UNII-80061L1WGD safe for nursing mother and child? Does UNII-80061L1WGD extracts into breast milk? Does UNII-80061L1WGD has any long term or short term side effects on infants? Can UNII-80061L1WGD influence milk supply or can UNII-80061L1WGD decrease milk supply in lactating mothers?
UNII-80061L1WGD lactation summary
- DrLact safety Score for UNII-80061L1WGD is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-80061L1WGD may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-80061L1WGD may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-80061L1WGD low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-80061L1WGD We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-80061L1WGD usage in lactation
No long-term adverse effects have been reported. However, it is excreted in large amounts into breast milk. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.
Answer by DrLact: About UNII-80061L1WGD usage in lactation
Limited information indicates that maternal UNII-80061L1WGD results in infant dosages much less than those given directly to neonates. UNII-80061L1WGD would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. However, because of its potential for causing hepatic enzyme inhibition, other drugs might be preferred.
UNII-80061L1WGD Possible Effects in Breastfeeding
Histamine H2-receptor blockade is known to stimulate prolactin secretion. In addition, UNII-80061L1WGD may have additional, nonspecific actions that stimulate prolactin secretion.[2] Oral UNII-80061L1WGD doses of 400 mg 4 times daily increased serum prolactin by 50 to 112% in 6 patients. UNII-80061L1WGD caused dose-related gynecomastia and galactorrhea in men and nonnursing women.[3][4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
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