Question

I am a breastfeeding mother and i want to know if it is safe to use Rofecoxib? Is Rofecoxib safe for nursing mother and child? Does Rofecoxib extracts into breast milk? Does Rofecoxib has any long term or short term side effects on infants? Can Rofecoxib influence milk supply or can Rofecoxib decrease milk supply in lactating mothers?

Rofecoxib lactation summary

Rofecoxib is unsafe in breastfeeding
  • DrLact safety Score for Rofecoxib is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Rofecoxib may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Rofecoxib may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Rofecoxib .
  • It is recommended to evaluate the advantage of not breastfeeding while using Rofecoxib Vs not using Rofecoxib And continue breastfeeding.
  • While using Rofecoxib Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Rofecoxib usage in lactation

Medication indicated for treatment of Arthritis, acute pain and Primary Dysmenorrhea. It acts by blocking the activity of enzyme cyclooxygenase (COX-2). Excretion into breast milk is insignificant. Withdrawn from the world market since 2004, because an observed higher risk for severe cardiovascular damage (myocardial infarction, ictus) among patients who were treated for longer than one year.

Alternate Drugs for Antiinflammatory and antirheumatic products, non-steroids and others specific. ATC M01A-C

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