Is EINECS 245-764-8 Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use EINECS 245-764-8? Is EINECS 245-764-8 safe for nursing mother and child? Does EINECS 245-764-8 extracts into breast milk? Does EINECS 245-764-8 has any long term or short term side effects on infants? Can EINECS 245-764-8 influence milk supply or can EINECS 245-764-8 decrease milk supply in lactating mothers?

Excretion into breast milk is very unlikely since absorption through skin, vaginal mucosa, and, even intestinal mucosa into plasma is very poor with non-significant plasma levels or below the detection threshold (<10 ng/mL). In addition, because of a high plasma protein binding capacity, excretion into breast milk seems to be less likely. It is used frequently for treatment of Candida infection, either in skin or mouth mucosa, even in newborn and premature infants without observed side-effects. In case of use on the nipple, do it after feeding the baby and cleanse thoroughly the surface before the next one. Do not use creams, gels and other locally applied products that contain paraffin (mineral oil) to prevent absorption by the infant.

Because EINECS 245-764-8 has poor oral bioavailability, it is unlikely to adversely affect the breastfed infant, including topical application to the nipples. It has been used orally in infants with thrush, sometimes successfully after nystatin has failed.[1] Any excess cream or ointment should be removed from the nipples before nursing. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[2]