Is UNII-Q3JTX2Q7TU Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use UNII-Q3JTX2Q7TU? Is UNII-Q3JTX2Q7TU safe for nursing mother and child? Does UNII-Q3JTX2Q7TU extracts into breast milk? Does UNII-Q3JTX2Q7TU has any long term or short term side effects on infants? Can UNII-Q3JTX2Q7TU influence milk supply or can UNII-Q3JTX2Q7TU decrease milk supply in lactating mothers?

It is a long-acting Benzodiazepine. Low excreted into breast milk. However, it may cause sedation and poor suction reflex in the infant mostly because of large or repetitive use in the newborn period. Low dose and short-term use is usually compatible with breastfeeding. Choose a short-acting and minimal effective drug dose specially when nursing a newborn. Watch out for somnolence and poor feeding of the infant. Bed-sharing is not recommended for mothers who are taking this medication.

UNII-Q3JTX2Q7TU is excreted into breastmilk and it and its active metabolite, norUNII-Q3JTX2Q7TU, accumulate in the serum of breastfed infants with repeated doses. Because the half-life of UNII-Q3JTX2Q7TU and norUNII-Q3JTX2Q7TU are long, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Other agents are preferred, especially while nursing a newborn or preterm infant. After a single dose of UNII-Q3JTX2Q7TU, as for sedation before a procedure, there is usually no need to wait to resume breastfeeding, although with a newborn or preterm infant, a cautious approach would be to wait a period of 6 to 8 hours before resuming nursing.

Three infants were breastfed from birth while their mothers were receiving UNII-Q3JTX2Q7TU 10 mg 3 times daily. The authors noticed no lethargy or hypoventilation in the infants during the 6-day observation period. The authors expressed concern that norUNII-Q3JTX2Q7TU may compete with bilirubin for hepatic glucuronide conjugation in the neonate.[1] A nursing mother was given UNII-Q3JTX2Q7TU 10 mg orally 3 times a day beginning on day 5 postpartum. Weight loss, lethargy and an EEG consistent with sedative effect in her 8-day-old was probably caused by UNII-Q3JTX2Q7TU or its metabolites in breastmilk.[7] Of 8 infants breastfed from birth during maternal UNII-Q3JTX2Q7TU therapy (dosages unspecified), 3 had mild jaundice during the first few days postpartum, although this was not thought by the authors to be unusual.[8] Sedation was reported in the breastfed newborn infant of a mother taking oral UNII-Q3JTX2Q7TU 6 to 10 mg daily if the infant was nursed within a few hours of a dose, but not if she nursed 8 or more hours after a dose. Infant sedation was probably caused by UNII-Q3JTX2Q7TU and its major metabolite in breastmilk.[4] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. About 10% of mothers took UNII-Q3JTX2Q7TU while breastfeeding and none reported sedation in her infant.[9] In a longitudinal study of women taking medications during breastfeeding, some mothers who were taking UNII-Q3JTX2Q7TU reported discontinuing breastfeeding because of drowsiness in their breastfed infants.[10]