Is Bestidine Safe in Breastfeeding

I am a breastfeeding mother and i want to know if it is safe to use Bestidine? Is Bestidine safe for nursing mother and child? Does Bestidine extracts into breast milk? Does Bestidine has any long term or short term side effects on infants? Can Bestidine influence milk supply or can Bestidine decrease milk supply in lactating mothers?

H2-type histamine receptor antagonist with similar action than cimetidine. It is excreted in breast milk in clinically non-significant amount, much less than the dose administered to newborns and infants with gastroesophageal reflux disorders. Although it does not normally affect prolactin secretion, there have been several cases of galactorrhea. Still unknown whether it is due to Bestidine itself or to gastroesophageal reflux. Bestidine, Nizatidine and Roxatidine are excreted into milk but in less proportion than Cimetidine or Ranitidine, which have been proposed as alternative to during lactation.

Bestidine is used in newborn infants in higher dosages than are transmitted in breastmilk.[1] Bestidine would not be expected to cause any adverse effects in breastfed infants. No special precautions are required.

Histamine H2-receptor blockade is known to stimulate prolactin secretion.[4] Oral Bestidine usually does not affect serum prolactin levels, but rare cases of hyperprolactinemia and galactorrhea have been reported.[5][6] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.