Question

I am a breastfeeding mother and i want to know if it is safe to use Kanamycin? Is Kanamycin safe for nursing mother and child? Does Kanamycin extracts into breast milk? Does Kanamycin has any long term or short term side effects on infants? Can Kanamycin influence milk supply or can Kanamycin decrease milk supply in lactating mothers?

Kanamycin lactation summary

Kanamycin is safe in breastfeeding
  • DrLact safety Score for Kanamycin is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Kanamycin is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Kanamycin does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Kanamycin safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Kanamycin usage in lactation

Aminoglycosides are poorly absorbed by the intestine. Large doses may affect intestinal flora. Be aware of the possibility of false negative results of bacterial cultures when the mother is on antibiotics. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Answer by DrLact: About Kanamycin usage in lactation

If kanamycin is required by the mother, it is not a reason to discontinue breastfeeding. Kanamycin is poorly excreted into breastmilk. Newborn infants apparently absorb small amounts of other aminoglycosides, but serum levels with typical three times daily dosages are far below those attained when treating newborn infections and systemic effects of kanamycin are unlikely. Older infants would be expected to absorb even less kanamycin. Because there is little variability in the milk kanamycin levels during multiple daily dose regimens, timing breastfeeding with respect to the dose is of little or no benefit in reducing infant exposure. Data are not available with single daily dose regimens. Monitor the infant for possible effects on the gastrointestinal flora, such as diarrhea, candidiasis (e.g., thrush, diaper rash) or rarely, blood in the stool indicating possible antibiotic-associated colitis.

Kanamycin Side Effects in Breastfeeding

Kanamycin was used as part of a six-drug regimen to treat a pregnant woman with multidrug-resistant tuberculosis during the first trimester of pregnancy and postpartum. The infant was breastfed (extent and duration not stated). At age 1.8 years, the child had failure to thrive, possibly due to tuberculosis contracted after birth, but was otherwise developing normally.[4]

Alternate Drugs

Neomycin(Safe)
Amikacin(Safe)
Kanamycin(Safe)
Linezolid(Low Risk)
Methicillin(Low Risk)
Ofloxacin(Safe)
Cefdinir(Safe)
Malathion(Low Risk)
Ritonavir(Unsafe)
Naftifine(Safe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Abacavir(Safe)
Cefoxitin(Safe)
Nevirapine(Low Risk)
Meropenem(Safe)
Dapsone(Low Risk)
Nelfinavir(Unsafe)
Famciclovir(Low Risk)
Enoxacin(Low Risk)
Cefotetan(Safe)
Capreomycin(Low Risk)
Rifaximin(Safe)
Neomycin(Safe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Ertapenem(Safe)
Indinavir(Unsafe)
Zidovudine(Low Risk)
Clindamycin(Low Risk)
Amantadine(Low Risk)
Levofloxacin(Low Risk)
Amikacin(Safe)
Nafcillin(Safe)
Econazole(Safe)
Tenofovir(Safe)
Valganciclovir(Low Risk)
Demeclocycline(Low Risk)
Cefixime(Safe)
Kanamycin(Safe)
Moxifloxacin(Low Risk)
Acyclovir(Safe)
Ganciclovir(Low Risk)
Lindane(Unsafe)
Quinine(Safe)
Cefepime(Safe)
Primaquine(Low Risk)
Efavirenz(Unsafe)
Saquinavir(Unsafe)
Aztreonam(Safe)
Atovaquone(Low Risk)
Didanosine(Unsafe)
Cefprozil(Safe)
Ofloxacin(Safe)
Cefdinir(Safe)
Methenamine(Unsafe)
Cefazolin(Safe)
Gatifloxacin(Low Risk)
Cefoxitin(Safe)
Mupirocin(Safe)
Enoxacin(Low Risk)
Cefotetan(Safe)
Capreomycin(Low Risk)
Neomycin(Safe)
Cefaclor(Safe)
Erythromycin(Low Risk)
Doxycycline(Low Risk)
Lomefloxacin(Low Risk)
Ertapenem(Safe)
Iodine(Unsafe)
Nalidixic Acid(Low Risk)
Clindamycin(Low Risk)
Levofloxacin(Low Risk)
Nafcillin(Safe)
Demeclocycline(Low Risk)
Cefixime(Safe)
Amikacin(Safe)
Moxifloxacin(Low Risk)
Kanamycin(Safe)
Cefepime(Safe)
Aztreonam(Safe)
Cefprozil(Safe)
Methicillin(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.