Question

I am a breastfeeding mother and i want to know if it is safe to use 2-Phenyl-1,3-propanediol dicarbamate? Is 2-Phenyl-1,3-propanediol dicarbamate safe for nursing mother and child? Does 2-Phenyl-1,3-propanediol dicarbamate extracts into breast milk? Does 2-Phenyl-1,3-propanediol dicarbamate has any long term or short term side effects on infants? Can 2-Phenyl-1,3-propanediol dicarbamate influence milk supply or can 2-Phenyl-1,3-propanediol dicarbamate decrease milk supply in lactating mothers?

2-Phenyl-1,3-propanediol dicarbamate lactation summary

2-Phenyl-1,3-propanediol dicarbamate is unsafe in breastfeeding
  • DrLact safety Score for 2-Phenyl-1,3-propanediol dicarbamate is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 2-Phenyl-1,3-propanediol dicarbamate may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 2-Phenyl-1,3-propanediol dicarbamate may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 2-Phenyl-1,3-propanediol dicarbamate .
  • It is recommended to evaluate the advantage of not breastfeeding while using 2-Phenyl-1,3-propanediol dicarbamate Vs not using 2-Phenyl-1,3-propanediol dicarbamate And continue breastfeeding.
  • While using 2-Phenyl-1,3-propanediol dicarbamate Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 2-Phenyl-1,3-propanediol dicarbamate usage in lactation

There is an increased risk of aplastic anemia and liver failure to the mother.

Answer by DrLact: About 2-Phenyl-1,3-propanediol dicarbamate usage in lactation

Because no information is available on the use of 2-Phenyl-1,3-propanediol dicarbamate during breastfeeding, and because it can cause potentially fatal hematologic and hepatic toxicities, authors of authoritative reviews recommend that breastfeeding not be undertaken during maternal 2-Phenyl-1,3-propanediol dicarbamate therapy until more safety data are available.[1][2]
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