Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-8VZV102JFY? Is UNII-8VZV102JFY safe for nursing mother and child? Does UNII-8VZV102JFY extracts into breast milk? Does UNII-8VZV102JFY has any long term or short term side effects on infants? Can UNII-8VZV102JFY influence milk supply or can UNII-8VZV102JFY decrease milk supply in lactating mothers?

UNII-8VZV102JFY lactation summary

UNII-8VZV102JFY is safe in breastfeeding
  • DrLact safety Score for UNII-8VZV102JFY is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-8VZV102JFY is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-8VZV102JFY does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-8VZV102JFY safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-8VZV102JFY usage in lactation

Excreted into breast milk in much lesser amount than that used for the treatment of Candida infection in the infant. Problems have not appeared in breastfed infants from treated mothers. Widely used for the treatment of breast pain due or allegedly due to Candida infection. In those cases of breast candidiasis where topical treatment fails, oral UNII-8VZV102JFY may be used at a dose of 200 mg for the first day to be followed by 100 mg daily for two weeks. The American Academy of Pediatrics rates it compatible with breastfeeding.

Answer by DrLact: About UNII-8VZV102JFY usage in lactation

UNII-8VZV102JFY is acceptable in nursing mothers because amounts excreted into breastmilk are less than the neonatal UNII-8VZV102JFY dosage.[1] Although no adequate clinical studies on UNII-8VZV102JFY in mastitis have been published, a survey of members of the Academy of Breastfeeding Medicine found that UNII-8VZV102JFY is often prescribed for nursing mothers to treat breast candidiasis, especially with recurrent or persistent infections.[2] Treatment of the mother and infant simultaneously with UNII-8VZV102JFY is often used when other treatments fail.[2][3][4][5] The most common maternal dosage regimen is 400 mg once, followed by 200 mg daily for at least 2 weeks or until pain is resolved,[6][7] although a study in Australia used a dose of 150 mg every other day until breast pain resolved.[8] The dosage of UNII-8VZV102JFY in breastmilk with these maternal dosages is not sufficient to treat oral thrush in the infant.

UNII-8VZV102JFY Side Effects in Breastfeeding

In a study of UNII-8VZV102JFY for treatment of lactation-associated thrush of the breasts, mothers took an average of 7.3 capsules (range 1 to 29 capsules) of 150 mg every other day until pain resolved. Seven of the 96 women reported side effects possibly caused by UNII-8VZV102JFY in their breastfed infants. These included flushed cheeks, gastrointestinal upset, and runny or mucous stools.[8]
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