Is UNII-O26FZP769L Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-O26FZP769L? Is UNII-O26FZP769L safe for nursing mother and child? Does UNII-O26FZP769L extracts into breast milk? Does UNII-O26FZP769L has any long term or short term side effects on infants? Can UNII-O26FZP769L influence milk supply or can UNII-O26FZP769L decrease milk supply in lactating mothers?
UNII-O26FZP769L lactation summary
- DrLact safety Score for UNII-O26FZP769L is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of UNII-O26FZP769L is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that UNII-O26FZP769L does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of UNII-O26FZP769L safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-O26FZP769L usage in lactation
Short-acting Benzodiazepine drug. Excretion into breast milk is non-significant (Whitelaw 1981, Summerfield 1985 , Lemmer 2007). No harmful effects on breastfed infants have appeared at a normal dose (Kelly 2012). Unusual and low doses of benzodiazepine are compatible with breastfeeding. Use a short-acting benzodiazepine and minimal effective dose as possible mostly in neonatal period. Follow-up for sedation and feeding ability of the infant. Bed-sharing is not recommended for mothers who are taking this medication.
Answer by DrLact: About UNII-O26FZP769L usage in lactation
UNII-O26FZP769L has low levels in breastmilk, a short half-life relative to many other benzodiazepines, and is safely administered directly to infants. Evidence from nursing mothers indicates that UNII-O26FZP769L does not cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.
UNII-O26FZP769L Side Effects in Breastfeeding
The newborn infant of a mother taking 2.5 mg of UNII-O26FZP769L orally twice daily for 5 days after delivery showed no signs of sedation.[2] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. Sixty-four mothers took UNII-O26FZP769L while breastfeeding and none reported sedation in her infant.[4]
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