Is N-Desmethyltemazepam Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-Desmethyltemazepam? Is N-Desmethyltemazepam safe for nursing mother and child? Does N-Desmethyltemazepam extracts into breast milk? Does N-Desmethyltemazepam has any long term or short term side effects on infants? Can N-Desmethyltemazepam influence milk supply or can N-Desmethyltemazepam decrease milk supply in lactating mothers?
N-Desmethyltemazepam lactation summary
- DrLact safety Score for N-Desmethyltemazepam is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N-Desmethyltemazepam is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N-Desmethyltemazepam does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N-Desmethyltemazepam safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-Desmethyltemazepam usage in lactation
Short-acting benzodiacepine. Diazepam active metabolite. Excreted into breast milk in non-significant level. No harm effects on breastfed infants have been shown. Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Check-up for infant sedation and feeding problems. Bed-sharing is not recommended for mothers who are taking this medication.
Answer by DrLact: About N-Desmethyltemazepam usage in lactation
N-Desmethyltemazepam has low levels in breastmilk, a short half-life relative to many other benzodiazepines, and is administration directly to infants. N-Desmethyltemazepam would not be expected to cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.
N-Desmethyltemazepam Side Effects in Breastfeeding
A woman with major depression was treated with N-Desmethyltemazepam and her breastfed infant was reportedly sedated. The dosage of N-Desmethyltemazepam, age of the infant and extent of nursing were not reported.[4] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. Two mothers took N-Desmethyltemazepam while breastfeeding and neither reported sedation in her infant.[5]
Alternate Drugs
Midazolam(Safe)
Lorazepam(Safe)
Chlordiazepoxide(Low Risk)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Flunitrazepam(Unsafe)
Oxazepam(Safe)
Alprazolam(Low Risk)
Lormetazepam(Safe)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Chlordiazepoxide(Low Risk)
Estazolam(Low Risk)
Flurazepam(Unsafe)
Temazepam(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Flunitrazepam(Unsafe)
Clonazepam(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Lormetazepam(Safe)
Alprazolam(Low Risk)
Lormetazepam(Safe)
Ketamine(Low Risk)
Chloral Hydrate(Low Risk)
Midazolam(Safe)
Zolpidem(Safe)
Estazolam(Low Risk)
Zaleplon(Safe)
Triazolam(Low Risk)
Flurazepam(Unsafe)
Lorazepam(Safe)
Chlordiazepoxide(Low Risk)
Eszopiclone(Low Risk)
Sodium Oxybate(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Butabarbital(Low Risk)
Quazepam(Unsafe)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Phenobarbital(Low Risk)
Secobarbital(Low Risk)
Flunitrazepam(Unsafe)
Propofol(Safe)
Oxazepam(Safe)