Question

I am a breastfeeding mother and i want to know if it is safe to use Z10-TR? Is Z10-TR safe for nursing mother and child? Does Z10-TR extracts into breast milk? Does Z10-TR has any long term or short term side effects on infants? Can Z10-TR influence milk supply or can Z10-TR decrease milk supply in lactating mothers?

Z10-TR lactation summary

Z10-TR is safe in breastfeeding
  • DrLact safety Score for Z10-TR is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Z10-TR is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Z10-TR does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Z10-TR safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Z10-TR usage in lactation

Short-acting benzodiacepine. Diazepam active metabolite. Excreted into breast milk in non-significant level. No harm effects on breastfed infants have been shown. Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Check-up for infant sedation and feeding problems. Bed-sharing is not recommended for mothers who are taking this medication.

Answer by DrLact: About Z10-TR usage in lactation

Z10-TR has low levels in breastmilk, a short half-life relative to many other benzodiazepines, and is administration directly to infants. Z10-TR would not be expected to cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.

Z10-TR Side Effects in Breastfeeding

A woman with major depression was treated with Z10-TR and her breastfed infant was reportedly sedated. The dosage of Z10-TR, age of the infant and extent of nursing were not reported.[4] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. Two mothers took Z10-TR while breastfeeding and neither reported sedation in her infant.[5]

Alternate Drugs

Clorazepate(Low Risk)
Oxazepam(Safe)
Alprazolam(Low Risk)
Midazolam(Safe)
Lorazepam(Safe)
Temazepam(Low Risk)
Meprobamate(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Oxazepam(Safe)
Clonazepam(Low Risk)
Alprazolam(Low Risk)
Midazolam(Safe)
Clobazam(Low Risk)
Lorazepam(Safe)
Estazolam(Low Risk)
Temazepam(Low Risk)
Flurazepam(Unsafe)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Quazepam(Unsafe)
Clorazepate(Low Risk)
Quazepam(Unsafe)
Butabarbital(Low Risk)
Phenobarbital(Low Risk)
Pentobarbital(Low Risk)
Clorazepate(Low Risk)
Secobarbital(Low Risk)
Oxazepam(Safe)
Propofol(Safe)
Alprazolam(Low Risk)
Ketamine(Low Risk)
Midazolam(Safe)
Chloral Hydrate(Low Risk)
Zolpidem(Safe)
Estazolam(Low Risk)
Zaleplon(Safe)
Triazolam(Low Risk)
Flurazepam(Unsafe)
Lorazepam(Safe)
Sodium Oxybate(Low Risk)
Eszopiclone(Low Risk)
Meprobamate(Low Risk)
Temazepam(Low Risk)
Butalbital(Low Risk)
Diazepam(Low Risk)
Nitrazepam(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.