Is WY-3498 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use WY-3498? Is WY-3498 safe for nursing mother and child? Does WY-3498 extracts into breast milk? Does WY-3498 has any long term or short term side effects on infants? Can WY-3498 influence milk supply or can WY-3498 decrease milk supply in lactating mothers?
WY-3498 lactation summary
- DrLact safety Score for WY-3498 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of WY-3498 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that WY-3498 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of WY-3498 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About WY-3498 usage in lactation
Short-acting benzodiacepine. Diazepam active metabolite. Excreted into breast milk in non-significant level. No harm effects on breastfed infants have been shown. Eventual and low dose use of benzodiacepines are compatible with breastfeeding. Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period. Check-up for infant sedation and feeding problems. Bed-sharing is not recommended for mothers who are taking this medication.
Answer by DrLact: About WY-3498 usage in lactation
WY-3498 has low levels in breastmilk, a short half-life relative to many other benzodiazepines, and is administration directly to infants. WY-3498 would not be expected to cause any adverse effects in breastfed infants with usual maternal dosages. No special precautions are required.
WY-3498 Side Effects in Breastfeeding
A woman with major depression was treated with WY-3498 and her breastfed infant was reportedly sedated. The dosage of WY-3498, age of the infant and extent of nursing were not reported.[4] In a telephone follow-up study, 124 mothers who took a benzodiazepine while nursing reported whether their infants had any signs of sedation. Two mothers took WY-3498 while breastfeeding and neither reported sedation in her infant.[5]
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