Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-359HUE8FJC? Is UNII-359HUE8FJC safe for nursing mother and child? Does UNII-359HUE8FJC extracts into breast milk? Does UNII-359HUE8FJC has any long term or short term side effects on infants? Can UNII-359HUE8FJC influence milk supply or can UNII-359HUE8FJC decrease milk supply in lactating mothers?

UNII-359HUE8FJC lactation summary

UNII-359HUE8FJC is safe in breastfeeding
  • DrLact safety Score for UNII-359HUE8FJC is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-359HUE8FJC is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-359HUE8FJC does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-359HUE8FJC safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-359HUE8FJC usage in lactation

Antiviral agent used for topical treatment of herpes of the lip. Famciclovir is its precursor drug which is used for systemic treatment. At latest update, relevant published data on excretion into breast milk were not found. After topical use, plasma levels are undetectable. Such property is the main reason by which it is not excreted into breast milk, In addition, a low oral bioavailability would impede the absorption from ingested milk toward the infant's plasma. Do not apply creams, gels and other products for topical use that would contain paraffin (mineral oil) on the breast to prevent ingestion by the infant. If necessary, apply UNII-359HUE8FJC after a feed and clean thoroughly with water before the next.

Answer by DrLact: About UNII-359HUE8FJC usage in lactation

Although there is no published experience with UNII-359HUE8FJC during breastfeeding, infant side effects are unlikely with maternal topical application to small areas of the mother's body away from the breast. Only water-miscible cream or gel products should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.[1]

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Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.