Question

I am a breastfeeding mother and i want to know if it is safe to use Phenindione? Is Phenindione safe for nursing mother and child? Does Phenindione extracts into breast milk? Does Phenindione has any long term or short term side effects on infants? Can Phenindione influence milk supply or can Phenindione decrease milk supply in lactating mothers?

Phenindione lactation summary

Phenindione is unsafe in breastfeeding
  • DrLact safety Score for Phenindione is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of Phenindione may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that Phenindione may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using Phenindione .
  • It is recommended to evaluate the advantage of not breastfeeding while using Phenindione Vs not using Phenindione And continue breastfeeding.
  • While using Phenindione Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Phenindione usage in lactation

One case of hematoma after surgical procedure in a child whose breastfeeding mother was receiving this drug.It is absorbed through the gastrointestinal tract, and unlike warfarin, large amounts have been detected in breast milk.

Alternate Drugs for Antithrombotic agents: Vitamin K antagonists. ATC B01AA

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.