Is Sugammadex Sodium Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Sugammadex Sodium? Is Sugammadex Sodium safe for nursing mother and child? Does Sugammadex Sodium extracts into breast milk? Does Sugammadex Sodium has any long term or short term side effects on infants? Can Sugammadex Sodium influence milk supply or can Sugammadex Sodium decrease milk supply in lactating mothers?
Sugammadex Sodium lactation summary
- DrLact safety Score for Sugammadex Sodium is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Sugammadex Sodium is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Sugammadex Sodium does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Sugammadex Sodium safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Sugammadex Sodium usage in lactation
A modified gamma-cyclodextrin that binds to rocuronium or vecuronium, reversing its neuromuscular blocking action. Used intravenously. Since the last update we have not found published data on its excretion in breast milk. Side effects are rare and mild.It is administered in single or isolated doses. Its high molecular weight makes it unlikely that it will pass into milk in significant amounts. Its low oral bioavailability would make it difficult its passage to the infant’s plasma through breast milk (EMA 2017).Sugammadex can be used during breastfeeding (EMA 2017)
Answer by DrLact: About Sugammadex Sodium usage in lactation
No information is available on the clinical use of sugammadex during breastfeeding. Because sugammadex is a large, highly polar molecule with a molecular weight of 2002, the amount in milk is likely to be very low and oral absorption by the infant is unlikely. Sugammadex is acceptable to use during breastfeeding.[1]
Alternate Drugs for Antidotes, chelating (Fe) & detoxifying (Onco) agents & other therapeutic products. ATC V03
Naloxone(Low Risk)
Deferoxamine(Low Risk)
Sugammadex(Safe)
Acetylcysteine(Safe)
Dimercaprol(Low Risk)
Flumazenil(Low Risk)
Ipecacuanha(Safe)
Methyltionine Chloride(Low Risk)
Dl-Methioninum(Low Risk)
Amyl Nitrite(Low Risk)
Protamine Sulphate(Low Risk)
Succimer(Low Risk)
Dmsa(Low Risk)
Bal(Low Risk)
Flumazepil(Low Risk)
Racemethionine(Low Risk)