Question

I am a breastfeeding mother and i want to know if it is safe to use HSDB 3925? Is HSDB 3925 safe for nursing mother and child? Does HSDB 3925 extracts into breast milk? Does HSDB 3925 has any long term or short term side effects on infants? Can HSDB 3925 influence milk supply or can HSDB 3925 decrease milk supply in lactating mothers?

HSDB 3925 lactation summary

HSDB 3925 is safe in breastfeeding
  • DrLact safety Score for HSDB 3925 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of HSDB 3925 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that HSDB 3925 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of HSDB 3925 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About HSDB 3925 usage in lactation

Drug which is commonly used in pediatric therapy even for newborn treatment. Excreted in high amount into breast milk although infant intake is reportedly lower than usual therapeutic dose. No side effects on breastfed babies have been reported. Increase of Prolactin levels has been shown, yet it does not induce galactorrhea.

Answer by DrLact: About HSDB 3925 usage in lactation

Although interpatient variability exists, the dose of HSDB 3925 in breastmilk is less than the dose used in newborn infants. Maternal HSDB 3925 would not be expected to cause any adverse effects in breastfed infants. No special precautions are required.

HSDB 3925 Side Effects in Breastfeeding

One 54-day-old breastfed infant had no observable adverse effects after maternal ingestion of HSDB 3925 150 mg every 12 hours for 2 days.[2]

HSDB 3925 Possible Effects in Breastfeeding

Histamine H2-receptor blockade is known to stimulate prolactin secretion.[3] HSDB 3925 in intravenous doses over 100 mg or during long-term oral use have increased serum prolactin in some studies, and rare cases of gynecomastia have been reported.[4][5][6][7][8] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.